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Junk DNA: A Journey Through the Dark Matter of the Genome is written by Nessa Carey. It is a general-readership science book on the emerging understanding of DNA regions once dismissed as “junk”.
For decades, around 98 per cent of human DNA was labelled “junk” because it does not code for proteins. This book examines how the effects and essential roles of these regions are only now coming into view, across topics ranging from rare genetic diseases and Down’s syndrome to viral infections and the ageing process.
It also reflects on a fast-developing and sometimes controversial area of science that has already led to practical outcomes, including a successful cure for blindness and the use of DNA fingerprinting to help save innocent people from death row. Drawing on the author of The Epigenetics Revolution, it introduces a subject presented as central to understanding human complexity and even the origins of life on Earth.
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